Remdesivir CAS:1809249-37-3-custom synthesis contract manufacturing
Remdesivir CAS:1809249-37-3
Structural Formula Remdesivir CAS:1809249-37-3
Product Name Remdesivir
Synonym Remdesivir APIs;Remdesivir APIs;Remdesivir APIs;Remdesivir
CAS No. 1809249-37-3
Molecular Weight See details
Specifications Upon request
Packing Sea or Airworthy packing
Material Safety Data Sheet Upon request
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       Product Name: Remdesivir
       Synonym: Remdesivir; GS-5734; GS 5734; GS5734, Prodrug of GS-441524; Prodrug of GS441524; Prodrug of GS441524;
       CAS#: 1809249-37-3 
       Chemical Formula: C28H36N5O8P 
       Exact Mass: 601.2301 
       Molecular Weight: 601.5968 
       IUPAC/Chemical Name: 2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[1,2-b]pyridazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
       
       
               Also, we are offering steps of Remdesivir intermediates:
       
               CAS:1355357-49-1
       
               CAS:1911578-98-7
       
               CAS:1355049-92-1
       
               CAS:1191237-69-0
       
               CAS:1191237-80-5
        
       Application:
       Remdesivir has been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, and MERS-coronavirus and Coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013–2016 West African Ebola virus epidemic crisis.
        
       Gilead Sciences has recently confirmed that it is demonstrating whether the experimental Ebola drug Remdesivir may cause a fight against a new coronavirus (2019-nCoV) emerging in China. The company said that "active discussions are underway with researchers and clinicians in the United States and China about the potential use of Remdesivir in therapy."
       Remdesivir, also known as GS-5734, is an experimental RNA polymerase inhibitor developed by Gilead Sciences in 2014 in collaboration with the Centers for Disease Control and Prevention (CDC) and the U.S. Army Medical Institute for Infectious Diseases Anthony Fossie, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health (NIH), stated in a comment on JAMA Network that SARS-CoV and MERS-CoV are being used as prototypes to develop treatment strategies for 2019-nCoV. "Broad-spectrum antivirals, such as Remdesivir, lopinavir / ritonavir and interferon, have shown promise against MERS-CoV in animal models and are eva1uating their activity against 2019-nCoV," he said.

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Has a first-class R & D team, rich experience in custom compound synthesis, good at synthesis of organic compounds such as chiral, heterocyclic, benzene rings.Strict quality control platform for strict quality identification of synthetic products.Our team is proficient in new route design and route optimization. With the skillful skills to solve problems and the high success rate of the project, we have the ability to provide our customers with the following high quality chemical custom synthesis services.The company team has 20 years of R & D, production and management experience and philosophy, and domestic and foreign market experience, and strive to create a high-efficiency, high-quality integrated chemical service platform to better serve domestic and foreign customers.Has a group of experienced researchers in the field of organic synthetic chemistry, with the ability to solve problems and troubleshoot.


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Experienced Reaction
AlkylationPolymerizationDiazotization
NeutrallzationSulfonationDecompose
NitrationEliminationEsterification
AdditionChlorinationSubstitution
DehydrogenationReductionHydrogenation
Oxidation
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